N-[2-[(3S,4R)-3-Fluoro-4-methoxy-1-piperidyl]-4-pyrimidinyl]-5-isopropyl-8-[(2R,3S)-2-methyl-3-[(methylsulfonyl)methyl]-1-azetidinyl]isoquinolin-3-amine

Name	BLU-945
Synonyms	BLU-945 N-[2-[(3S,4R)-3-Fluoro-4-methoxy-1-piperidyl]-4-pyrimidinyl]-5-isopropyl-8-[(2R,3S)-2-methyl-3-[(methylsulfonyl)methyl]-1-azetidinyl]isoquinolin-3-amine
CAS	2660250-10-0

Molecular Formula	C28H37FN6O3S
Molar Mass	556.7
Appearance	Solid
Storage Condition	4°C, protect from light *In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
In vitro study	BLU-945 has inhibitory activity against the EGFRm/T790M double and EGFRm/T790M/C797Striple mutants with IC50 value range from 1.2-4.4 nM. BLU-945 (0- 10 mM, 4 h) inhibit EGFR phosphorylation in the EGFR L858R/T790M/C797S, and EGFR ex19del/T790M/C797S mutant cell lines. for reference only.

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CAS: 2660250-10-0
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Product Name: EAI-045 Impurity 2 Request for quotation
CAS: 2660250-10-0
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Email: 2853786052@qq.com
Mobile: 86+15671228036
QQ: 2853786052

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N-[2-[(3S,4R)-3-Fluoro-4-methoxy-1-piperidyl]-4-pyrimidinyl]-5-isopropyl-8-[(2R,3S)-2-methyl-3-[(methylsulfonyl)methyl]-1-azetidinyl]isoquinolin-3-amine Request for Quotation